A. The Sefer Shalmei Yehudah (10:15) on Hilchos Muktzah writes, in the name of HaRav Elyashiv, Shlita, that, although generally medicines that you were not taking before Shabbos are Muktzah to move or handle, certain “over-the-counter” medications such as Tylenol, Aspirin, Acomil (in Israel) may not be Muktzah, because they are so widely used by the multitude, and accordingly can be handled in a regular manner on Shabbos.
B. The Sefer Shabbos B’Sifarta writes that L’Chatchila one should not use tissues or cut toilet paper which has specific designs, as this constitutes Mochek D’Rabanan (see Shulchan Aruch, Orach Chaim 336; Mishne Berurah Seif Katan 27). The author of the Sefer, HaRav Avrohom Adas, Shlita, of Yerushalayim writes that HaRav Chaim Kanievsky, Shlita, told him that Bi’shas Hadechak (in case of extreme necessity), one can be lenient.
C. In the same Sefer, HaRav Adas writes that on Shabbos one may not return a drawer that has fallen or been taken out of a large wall unit, or a shelf in large clothing closet (Boneh). Please consult with your Rav as to how this may affect a particular situation that you may have in your home.
D. Also relating to Boneh, HaRav Adas writes that one should not make shapes out of paper such as planes or ships, or shape melons into designs (such as baskets or boats).